Microtubules Lab Report Example | Topics and Well Written Essays - 2750 words

Microtubules - Lab Report ExampleThis fundamental interaction, revealed by the structure, is branded the EB1-like motif and there is possibility that the binding interaction of CLIP family depends on this. Intuitively, considering that CLIP experiences binding at the acidic tail of tubulin, it is also possible that the acidic tail of EB1 also provides the same condition allowing for binding.12One of the important parts of the cell micro skeleton is the microtubules. The dynamics of microtubules is a very significant feature of cell control and cell morphogenesis. fit to research carried out recently, microtubules argon attributed with the role of maintaining intrinsic cell length control. Meanwhile, even after the development of a model that describes the MT dynamics that are associated with the control of cell length, elucidation of the spatial variability of MT nucleation is yet to occur.This intromission is a case of an investigation on the dynamics that are associated with nucl eation of microtubules. This presentation particularly refers to a Hela cell that has no visible chromosome which was videoed after aligning itself along a track of micro patterned fibronectin. This presentation also valued to find out the quantitative distribution of catastrophes and velocities inside the cells cortical and non-cortical regions. It also sought to investigate the spatial distribution of the microtubule nucleation that had resulted.According to the results obtained, parsimoniousness of microtubule nucleation could not be considered random as it was concentrated in particular regions of the cell. Also, the results showed that the cortical actin was instrumental in triggering the nucleation rate. The rate slowed down after the cortical actin floor was removed. After further examination of the microtubule lifetimes among the case and the control, it was found out that the slowing of nucleation rate could be attributed to the slowing down of the microtubule catastroph e rate, in the